Nebivolol is a cardioselective beta adrenoblokatorom III generation with vasodilating properties. It has antihypertensive, antianginal and antiarrhythmic action.Nebivolol slows the heart rate (HR) and lowers blood pressure at rest and during exercise, reduces end-diastolic left ventricular pressure, reduces the total peripheral vascular resistance, improves diastolic cardiac function (reducing end-diastolic left ventricular filling pressure) increases the ejection testosterone cypionate till salu fraction. Selectively and competitively blocks synaptic and post-synaptic beta-adrenergic receptors, making them inaccessible to catecholamines release modulates endothelial vasodilator factors nitric oxide (NO). Nebivolol is a racemate consisting of two enantiomers: SRRR-nebivolol (D-nebivolol) and the RSSS -nebivolola (L-nebivolol), which combines ...
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